Supplement · Brain health technique
Apigenin
Evidence grade: Context Dependent
A flavonoid found in chamomile, parsley, celery, and citrus fruits, sometimes used as a supplement for its calming, antioxidant, and hormone-modulating effects.
- Practice
- Supplement
- Principle
- Nourishment
- Tactic
- Neurochemical & Synaptic Support
- Evidence grade
- Context Dependent
- Strength of evidence
- Medium
- Cost
- Medium
- Effort
- Low
- Time commitment
- Low
How to practice Apigenin
If used, take 25–50 mg/day in the evening with food or as chamomile tea before bed. Avoid combining with sedatives without medical supervision. Benefits may be subtle and accumulate over time. Dietary intake from herbs and teas is generally sufficient for most.
The evidence behind Apigenin
Apigenin binds to benzodiazepine receptors, producing mild calming and sleep-promoting effects. Animal studies show reduced neuroinflammation and enhanced neurogenesis. Human data are minimal, mostly small pilot trials for anxiety and menopause symptoms. Safety profile appears good; main limitation is poor bioavailability.
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