Supplement · Brain health technique

Melatonin

Evidence grade: Context Dependent

Illustration for Melatonin

A hormone produced by the pineal gland that regulates circadian rhythms and sleep–wake timing. Supplements are synthetic and available in immediate or extended-release forms.

Practice
Supplement
Principle
Nourishment
Tactic
Mood, Sleep & Stress Modulators
Health domains
hormonal
Evidence grade
Context Dependent
Strength of evidence
Medium
Cost
Medium
Effort
Low
Time commitment
Low

How to practice Melatonin

For sleep onset, use 0.3–1 mg 30–60 minutes before bed.. Lower doses mimic natural physiology better than high ones. Maintain darkness and reduce screen exposure for best results. Use intermittently, not indefinitely.

The evidence behind Melatonin

Melatonin helps initiate sleep and align circadian timing, especially useful for jet lag, shift work, or delayed sleep phase. Meta-analyses confirm reduced sleep latency and improved onset consistency but minimal effect on sleep depth. Tolerance does not develop, though overdosing can cause grogginess or vivid dreams.

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