
Key takeaways:
Featured Biomarker
Homocysteine: A Key Marker for Cognitive Health
What it is: Homocysteine is an amino acid linked to increased risk of Alzheimer's and other forms of dementia.
Why it matters: High homocysteine can lead to oxidative stress and inflammation, contributing to damage in blood vessels and brain cells. Studies, like the VITACOG study, have shown that elevated homocysteine is an independent risk factor for cognitive decline. By lowering homocysteine, participants decreased their rate of brain shrinkage by 50%!
How to improve: Consider methylated B vitamins, especially B6, B9, and B12, which help reduce homocysteine levels and support brain health. Regular monitoring and targeted supplementation can make a significant difference in reducing this risk factor for dementia.
Peter Attia once referred to this as having a lottery ticket in your back pocket and not knowing it. This is one of the few areas in brain health where a quick win is possible!
BETTERBRAIN HACK
The Power of a Cold Bedroom
Did you know that maintaining a cool bedroom temperature at night can provide significant benefits for your brain health?
Hack: By setting your AC system to cool your bedroom to 65-68°F in the evening, you can optimize your sleep quality and support better cognitive function.
How it works:Your body's temperature naturally lowers during sleep, but keeping the bedroom too warm can increase your core body temperature. This higher core temperature can actually reduce the amount of time you spend in restorative REM sleep, which is crucial for memory consolidation and overall brain health.
The best part? This simple lifestyle adjustment is a low-cost, low-effort intervention with potentially significant impacts on your cognitive resilience and daily mental performance.
Read more about this brain health hack here, or give it a try and see how a cool bedroom can give your brain the optimal conditions to thrive.
CONTENT CORNER
Simple Steps to Protect Your Brain | NPR Health
Bottom Line: Simple daily habits can cut your risk of memory loss and depression by up to 33%. A new scoring system helps track which habits matter most.
About the article: NPR highlights a practical tool developed at Mass General Hospital - the brain care score - that helps people track 12 daily habits that protect brain health. The score looks at things we can all control, such as: sleep, exercise, diet, social connections, and stress management.
Real Results: Ruth Bernstein, a mom of two, uses the score daily: "It's super helpful. I check: Did I get my steps in? How's my sleep? Am I managing stress?" At a recent party, she enjoyed one glass of wine but skipped a second, knowing that limiting alcohol improves her score.
Quick Ways to Help Your Brain:
- Limit alcohol to less than 4 drinks per week
- Add leafy greens and healthy fats to meals
- Take a daily walk
- Stay connected with friends and family
- Get enough sleep
- Manage blood pressure
The Good News: Even small changes add up. Each 5-point increase in your score lowers your risk of late-life depression by 33% and dementia by 27%. Even if you have family history of these conditions, healthy habits can still help protect your brain.
BetterBrain Takeaway: Small, daily habits add up to major brain health benefits. Through our biomarker testing and lifestyle assessment, we help identify the areas where simple changes can have the biggest impact on your brain health. These personalized insights make it easier to focus your efforts where they matter most.

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