The latest in brain health

An 8,323-person trial found that lowering Lp(a) with pelacarsen did not reduce cardiovascular events. Here is what that does and does not change.

The 5 recommendations that appear most often in BetterBrain coaching plans, what the evidence says, and how to know which matters most for you.

pTau-217 is the Alzheimer's blood test making headlines. Here's what an elevated result actually means, how the tests differ, and what to do next.

A single infusion lowered LDL cholesterol by up to 62% and held it there for 18 months. It is years from a clinic. The target it aims at, your lipid h

Here is what the research says about insulin resistance and long-term brain health.

Generic brain health advice only goes so far. Learn how labs, wearable data and your health history can help BetterBrain deliver personalized guidance

Knowing what to do is not the same as doing it, and a new trial put a number on the gap

Our Chief Science Officer, Dr. Tommy Wood, joined Andrew Huberman on the Huberman Lab podcast to talk about how to keep learning and stay sharp at...

These are the six takeaways worth acting on.

Every technique in your BetterBrain plan is now linked to the research behind it: roughly 1,500 studies, mapped to your practices & biomarkers.

This week, we're exploring stress and brain health: what chronic stress does to your hippocampus (your brain's memory center), how mindfulness and...

Exercise snacks. Short, two-minute movement breaks sprinkled throughout the day, designed to keep your body active and your brain engaged without...

The therapy, called VERVE-102, targets a gene called PCSK9. PCSK9 is a protein that reduces your liver’s ability to clear LDL cholesterol from...

The Glymphatic System: Why Deep Sleep Is Your Brain's Best Cleanup Tool

The first S, Stimulation, is the one that surprises people. Tommy’s argument is that the brain, like muscle, needs ongoing challenges to maintain...

CRP or C-reactive protein is made by your liver in response to inflammation anywhere in your body. The "hs" stands for "high-sensitivity," which...

Maggie works with clients across the metabolic-health side of our client base. The trend she keeps seeing: HbA1c and fasting insulin numbers...

The research, called the Follow-Interventions-Trials (FIT) project, pulled participants from four earlier 18 to 24 month lifestyle randomized...

Is Resistance Training Best for Brain Health?

Bottom line: Researchers at UC San Francisco just discovered that when you exercise, your liver releases an enzyme called GPLD1 that travels to...

Meet Ana Hernandez, RD: Brain Health Coach

Sardinia is one of five validated Blue Zones, geographically defined areas with disproportionately high concentrations of people living past 100....

What's Actually Happening in Your Brain

From the beginning, we've believed in making brain health science accessible. Our mission is to empower every person to take charge of their brain...

The Nature Study: What It Actually Shows

What it is: The Omega-3 Index measures the percentage of EPA and DHA in your red blood cell membranes. It reflects your omega-3 status over the...

The Basics: What Is Cholesterol?

Your brain contains 25% of your body's cholesterol, yet blood cholesterol and brain cholesterol operate as two completely separate systems. We break d

Meet Sarah Ferreira, MS, MPH, RD, IFNCP: Brain Health Coach

What it is: Cognitive reserve refers to your brain's resilience to neuropathological damage. It's influenced by factors like education,...

Meet Wendy Pietri, BSN RN: Brain Health Coach

The Findings: Prevention, Intervention, and Treatment

The Bottom Line: Gut health is one of BetterBrain's 10 core systems because of the gut-brain axis, a bidirectional communication system where the...

Bottom Line: APOE4 is a significant genetic risk factor for Alzheimer's, but it's not deterministic. We've talked before about how environmental...

Background: Nancy (blinded name for privacy), a 57-year-old retiree, came to BetterBrain with concerning family history and multiple risk factors...

Bottom Line: While 5g of creatine monohydrate is the standard recommendation for athletic performance, emerging evidence suggests 10g daily may be...

For this week's newsletter, we're diving in a little deeper to why sleep matters. Dr. Matthew Walker explains the specific mechanism connecting...

Bottom Line: The FDA is removing black box warnings from HRT products after comprehensive scientific review. What happened: On November 10, 2025,...

Background: Amit (blinded name for privacy) a 42-year-old professional, came to BetterBrain not because he felt unwell, but because he wanted to...

Bottom Line: A comprehensive systematic review published in the British Journal of Sports Medicine found that exercise snacks, described as brief...

Bottom Line: This systematic review and meta-analysis, published in the journal Nutrients, reveals that added sugar consumption consistently...

Background: Joan (blinded name for privacy), 59, came to BetterBrain with something many of us worry about: a family history of dementia. She...

About Ben and his book: Dr. Ben Rein is pretty phenomenal: a Stanford neuroscientist with over 20 published papers on social behavior and an...

About the episode: This isn't your typical fitness podcast. Peter assembled three of the most respected names in strength and conditioning to...

Bottom Line: Peter Attia's comprehensive approach to bone health reveals why strong bones aren't just about preventing fractures—they're...

This week we have two complementary hacks for you as we transition between seasons. Think of them as yin and yang for your nervous system—each...

Unlike other biomarkers we've covered, APOE isn't something you can directly improve—but it might be the most important piece of information you...

What it is: Your Brain Score is a single number that combines data from multiple assessments to give you a comprehensive view of where you stand...

Over the coming weeks, we'll highlight more of these powerful tools in our newsletters; but this week, we're starting with two of our foundational...

TSH is a crucial biomarker for brain health that's often tested for in standard medical care. Produced by your pituitary gland, TSH regulates...

What it is: Sleep quality encompasses not just duration, but the depth and consistency of your sleep cycles. Quality sleep is essential for memory...

This week, we'll explore the powerful connection between metabolic health and brain function. We'll dive into HbA1c as a key biomarker for...

This week, we're exploring the critical connections between inflammation and brain health: how inflammatory markers reveal your cognitive risk...

Bottom line: Nature's feature on blood-based Alzheimer's testing examines how companies like BetterBrain are disrupting traditional healthcare...

This week, we're exploring three powerful physical approaches to brain health: how high-intensity interval training provides unique cognitive...

This week, we're diving into metabolic health and its crucial role in brain function. Learn about the strategic timing of protein intake for...

This week, we're exploring three key players in brain health: how moderate-intensity activities like tennis or pickleball can enhance cognitive...

This week, we're diving into the science of cellular health and aging - from rapamycin's potential to revolutionize how we think about longevity,...

This week, we're unpacking the science behind ApoB (and why it matters for your brain), sharing an inspiring member story about taking control of...

This week, we're exploring three fascinating aspects of brain health: how checking your iron stores might reveal important clues about cognitive...

What it is: High-sensitivity C-reactive protein (hs-CRP) is a marker of low-level, systemic inflammation in the body. Why it matters: Elevated...

What it is: HRV measures the variation in time between heartbeats and is a marker of your body's resilience and stress response. Why it matters:...

What it is: Homocysteine is an amino acid linked to increased risk of Alzheimer's and other forms of dementia. Why it matters: High homocysteine...

Do you know what's in your fish oil? Learn how DHA and EPA reduce Alzheimer's risk by supporting brain health and mitigating inflammation.

Homocysteine is an inflammatory marker that poses a severe threat to brain health. Luckily, there's an easy fix anyone can implement.

Rapamycin's winding path to mainstream use is showing promise as a longevity drug, and may soon change the way we approach brain health.

Thinking with your stomach? Turns out we all do it - the way you treat your gut microbiome influences not just your GI system, but also your brain.

Your metabolic health may not be optimal, even if you don't have diabetes. Learn how you can improve your metabolic health to protect your brain.

The time in between individual heartbeats is more meaningful than you may think.

CBT is a powerful tool for dementia prevention, which can help manage risk factors which include and go beyond mental health.

Air pollution may elevate Alzheimer's risk - find out how PM2.5 particles impact brain health.

Can stepping into a sauna actually "incinerate" your Alzheimer's risk? Let's explore the intriguing connection between saunas and brain health.

Unpacking the complex reasons why Alzheimer's affects women twice as much as men.

You have a ~25% chance of carrying this Alzheimer's risk gene - is it worth testing for?

The rise of amyloid blood tests may permanently change the way we assess Alzheimer's risk, but we are early.