Non-Modifiable
Genetic
APOE Genotype
Available as add-on
Why we test it
The APOE gene codes for a protein involved in cholesterol transport and fat metabolism. It has three major variants: E2, E3, and E4. The E4 variant is strongly correlated with a higher risk of developing Alzheimer's, while E2 appears protective. E3 is considered neutral. While APOE status is a potent risk factor, it is not deterministic. Environmental and lifestyle factors play a vital role in the onset and progression of Alzheimer's.
BetterBrain target
e3/e3 (lowest risk genotype)
The strongest known genetic risk factor for late-onset Alzheimer's. One-time test that enables personalized prevention.
What you Can do
- APOE-tailored diet (lower saturated fat for e4)
- Aerobic cardio training
- Quality sleep
- Omega-3 (DHA)
- Early and aggressive risk factor management
Test what matters for your brain and get a personalized action plan in a BetterBrain Program.
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